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Search Results - cancer

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CBL Targeted Therapeutics
BACKGROUND Myeloproliferative neoplasms such as acute myeloid leukemia (AML) are cancers of the bone marrow and blood. Incidence of AML range from 3–8 cases per 100,000 globally, predominantly in United States and Japan. Standard of care therapies include chemotherapy and allogeneic stem cell transplantation to help prolong remission. However,...
Inventor(s): Jane McGlade
Categories: Technology Classifications > Platform Technologies
Keyword(s): AML, cancer, drug discovery, leukemia, myeloproliferative neoplasms, small molecule therapeutics
Treating primary brain cancer using an ion channel complex-targeting peptide
BACKGROUND Glioblastoma (GBM) is the most common and aggressive brain cancer, and accounts for 60% of adult brain tumours. The median survival of adult GBM patients is 15 months, where the standard-of-care is a combination of surgery, radiation, and chemotherapy using the DNA alkylating agent temozolomide (TMZ), which extends patient survival by...
Inventor(s): Xi Huang
Categories: Technology Classifications > Therapeutics
Keyword(s): cancer, glioblastoma, ion channel, peptide therapy
ML-based RNA analysis for cancer diagnosis, prognosis, and therapy guidance applications
BACKGROUND Cancer is the second leading cause of death globally, accounting for nearly 10 million deaths and billions of dollars in healthcare expense. Accurate and early diagnosis of cancer is critical to determine precision treatment plans, improve patient outcomes, decrease morbidity, and decrease the financial burden of cancer. DNA sequencing...
Inventor(s): Adam Shlien
Categories: Technology Classifications > Diagnostics
Keyword(s): amplification, biomarker, cancer, diagnostics, hypermutant, tumor